Off the top of my head, I don't know of any current, pop-culture buzzwords that I absolutely despise. This is probably because I, as a general rule, completely ignore the type of people who would say things like "incentivize" with any hint of seriousness. If you're being funny? That's completely different. I tend to make up words myself from time to time... Or use really big ones... But rarely with a straight face.
I do know that in the years immediately following 9-11, I thought "homeland" was the silliest word ever. Of course, that could have been because of the two people who said it the most -- George W. Bush and Tom Ridge. Strangely, I always thought the latter was far dumber than the former. Even now, I'm not a big fan of homeland. But, again, it's probably because of the context of the word and what it's come to mean -- blue-shirted security guards at the airport who seem to hate me as much as they hate their job.
Honorable mention would be "24/7." For some reason, that used to drive me bat shit, but I can't begin to tell you why. My hatred has since subsided. I've even caught myself saying the phrase every now and then. Maybe that means there is hope for homeland.